My Youtube or other video won’t play on my Windows computer and Apogee interface, how can I resolve this?

If Youtube or other audio/video playback apps don’t work while your DAW is open, then there is most likely a sample rate mismatch between the DAW session and the WDM sample rate (i.e the System sample rate set in the Control Panel Sound Playback Properties Advanced). Set the System sample rate to match the rate of your DAW session.